No worries, it's not rude at all! I have no idea myself about this bug, it seems so random.
I remember once it happened when I tried to put plants in my box to sell them. I opened inventory to empty it and it froze.
Another time I think I just left Narbell Farm, picked a plant and opened inventory to eat strawberries cuz I was lacking space. I clicked on them but nothing happened, and the inventory didn't respond.
The only things both incidents have in common is full inventory and the fact I had walked around the map prior to it. Also, it never occured during my ventures to mines (and I basically live there), town or swamp, only when I was picking plants in the west.
The last thing I should add is that I can hear the background sounds and click of buttons normally. I just can't interact with anything.